More than 2,000 positions related to global health are being cut from the Johns Hopkins University after the Baltimore institution saw $800 million in federal grants disappear, a spokesperson confirmed Thursday.

Most of the layoffs will impact international employees, with 1,975 positions eliminated across 44 countries, along with 247 jobs in the U.S.

Local and international health research efforts are already winding down as the university braces for even more potential cuts.